MEDIPLEX DIETARY SYSTEM WORKS BETTER THAN OTHER DIET PLANS

Context : We have compared popular diets, particularly those low in carbohydrates, diet for weight loss to check the effectiveness of Mediplex System Vs other diets.

Objective:  To compare 5 weight-loss diets representing a spectrum of low to high carbohydrate intake for effects on weight loss and related metabolic variables.

Design, Setting, and Participants 

We conducted twelve-month randomized trial conducted in the   India from November 2009 to October 2010 among 352 free-living, overweight/obese (body mass index, 27-40) nondiabetic, premenopausal women.

Intervention  Participants were randomly assigned to follow the Mediplex (77), Atkins (n = 77), Zone (n = 79), LEARN (n = 79), or Ornish (n = 76) diets and received weekly instruction for 2 months, then an additional 10-month follow-up.

Main Outcome Measures The primary outcome was weight and inch loss at 12 months. Secondary outcomes included lipid profile (low-density lipoprotein, high-density lipoprotein, and non–high-density lipoprotein cholesterol, and triglyceride levels), percentage of body fat, waist-hip ratio, fasting insulin and glucose levels, and blood pressure. Outcomes were assessed at months 0, 2, 6, and 12.

Results  Weight loss was greater for women in the Mediplex diet group compared with the other diet groups at 12 months, and mean 12-month weight loss was significantly different between the Atkins and Zone diets (P<.05). Mean 12-month weight loss was as follows: Mediplex −9.7 kg (95% confidence interval [CI], −11.3 to −7.1 kg),  Atkins, −4.7 kg (95% confidence interval [CI], −6.3 to −3.1 kg), Zone, −1.6 kg (95% CI, −2.8 to −0.4 kg), LEARN, −2.6 kg (−3.8 to −1.3 kg), and Ornish, −2.2 kg (−3.6 to −0.8 kg). Weight loss was not statistically different among the Zone, LEARN, and Ornish groups. At 12 months, secondary outcomes for the Mediplex group were far better than the other diet groups.

 

 

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